研究成果总览
以下为课题组2023年成立以来发表的主要学术论文：
56. Zhenhao Shuai#, Tao Yu#, Bo Zhang, Chufan Ren, Liansheng Wang, Xiaoming Jiang*, Linjin Li*, and Jianwei Shuai*. YOLO-Light: Automatic Lightweight You-Only-Look-Once Generation in Different Scenarios Through NeuroEvolution. IEEE Transactions on Evolutionary Computation. 2025 in press (IF=12.0)
55. Xu Xu, Huagen Li, Hai Lin, Qichao Li, Yuenan Liu, Weijun Huang, Jundong Yang, Niannian Li, Zhenfei Gao, Shengming Wang, Hangdong Shen, Wenjun Xue,Haolin Yuan, Wei Wang, Jianwei Shuai, Junli Liu, Shankai Yin, Feng Liu.
MIF-mediated crosstalk between THRSP hepatocytes and CD74 lipid-associated macrophages in hepatic periportal zone drives MASH.
Hepatology, 2025 accepted, (IF = 15.8)
MIF-mediated crosstalk between THRSP hepatocytes and CD74 lipid-associated macrophages in hepatic periportal zone drives MASH.
Hepatology, 2025 accepted, (IF = 15.8)
54. Wei Wu, Xin Yang, Chenggui Yao,Ou Liu, Qi Zhao, Jianwei Shuai，E-SegNet: E-shaped Structure Networks for Accurate 2D and 3D Medical Image Segmentation，Research. 2025 (IF = 10.7)
53. Junpeng Xu, Chaohui Guo, Guangshuai Zhou, Haoman Chen, Peng Dai, Chonghui Tang, Shih-Ho Lin, Chen Zhang, Fanxuan Chen, Na Dong, Caiyan Li, Jie Pan, Xianzhen Chen, Ping Wu, Shengcun Li, Lihua Luo, Xiaokun Li, Jianwei Shuai, Shan-hui Hsu, Zhouguang Wang，An antioxidative injectable chitosan hydrogel based on tannic acid modified dialdehyde polyurethane nano-crosslinker targeting RIPK1 to regulate neuroinflammation for amelioration of Parkinson’s disease, Biomaterials 2025 (IF = 12.9)
52. Zhilong Liu, Fei Xu, Hong Qi, Jun Jin, Jiaju Jiang, Jianwei Shuai, and Xiang Li, Deciphering the 1 physical properties of cell fate decision making in mTOR signaling, PHYSICAL REVIEW E, 2025, 00, 004400, DOI: 10.1103/tgzc-vr4q, (IF = 2.4)
51. Qi-Chao Li, Hai Lin, Peng Wang, Qiutong Dong, Kun Wang, Jian-Wei Shuai, and Fang-Fu Ye, Analysis of spatiotemporal dynamic patterns of gene expression during mouse embryonic development based on Moran’s I and spatial transcriptomics, Chin. Phys. B, 2025, 34, 088703, DOI: 10.1088/1674-1056/ade427 (IF = 15.0)
50. Jing Wang, Zihao Sun, Huaicheng Chen, GaoWang, Duyu Chen, Guo Chen, Jianwei Shuai, Mingcheng Yang, Yang Jiao, and Liyu Liu, Hyperuniform Networks of Active Magnetic Robotic Spinners, Physical Revies Letters 2025, 134: 248301, DOI: 10.1103/z2rp-21xn (IF = 9.0)
49. Ruoyun Wang, Fanxuan Chen, Haoman Chen, Chenxing Lin, Jincen Shuai, Yutong Wu, Lixiang Ma, Xiaoqu Hu, Min Wu, Jin Wang, Qi Zhao, Jianwei Shuai, JingyePan. Deep Learning in Digital Breast Tomosynthesis: Current Status, Challenges and Future Trends. MedComm, 2025, 6: e70247, https://doi.org/10.1002/mco2.70247 (IF = 10.7)
48. Yuan Li, Huiqin Chen, Qiaofeng Shen, Yingshuang Liu, Pingping Li, Yuqi Ma, Yugang Wang, Shengkai Li, Xueqing Yan, Liyu Liu, Jianwei Shuai, Min Wu, Qi Ouyang, Feng-Ming (Spring) Kong, Gen Yang, Fragment autoantigens stimulated T-cell-immunotherapy (FAST) as a fast autologouscancer vaccine. Advanced Science,2025, 25: 2502937 1-16. https://doi.org/10.1002/advs.202502937, (IF = 14.1)
47. Suwen Wei, Yuer Lu, Peng Wang, Qichao Li, jianwei shuai, Qi Zhao, Hai Lin and Yuming Peng. Investigation of cell development and tissue structure network based on natural Language processing of scRNA-seq data. Journal of Translational Medicine, 2025, 23: 264. https://doi.org/10.1186/s12967-025-06263-2 (IF = 7.5)
46. Shiyang Wang, Xi Wu, Wenxin Bi, Jiuzhi Xu, Liyuan Hou, Guilin Li, Yuwei Pan, Hanfu Zhang, Mengzhen Li, Sujuan Du, Mingxin Zhang, Di Liu, Shuiling Jin, Xiaojing Shi, Yuhua Tian, Jianwei Shuai, Maksim Plikus, Moshi Song, Zhaocai Zhou, Lu Yu, Cong Lv, and Zhengquan Yu, ROS-induced cytosolic release of mitochondrial PGAM5 promotes colorectal cancer progression by interacting with MST3, Nature Communications. 2025, 16, 1406. https://doi.org/10.1038/s41467-025-56444-2 (IF =15.7 )
45. Xin Yang, Yang Wang, Ye Lin, Mingxuan Zhang, Ou Liu, Jianwei Shuai, Qi Zhao, A multi-task self-supervised strategy for predicting molecular properties and FGFR1 inhibitors, Advanced Science, 2025, 2412987 1-14. DOI: 10.1002/advs.202412987 (IF = 14.1)
44. Zhilong Liu, Hai Lin, Xiang Li, Hao Xue, Yuer Lu, Fei Xu, Jianwei Shuai, The network structural entropy for single-cell RNA sequencing data during skin aging, Briefings in Bioinformatics, 2025, 26: bbae698, https://doi.org/10.1093/bib/bbae698 (IF = 7.7)
43. Xin Yang, Jianqiang Sun, Bingyu Jin, Yuer Lu, Jinyan Cheng, Jiaju Jiang, Qi Zhao, Jianwei Shuai, Multi-task aquatic toxicity prediction model based on multi-level features fusion, Journal of Advanced Research, 2025, 68: 477-489, doi: 10.1016/j.jare.2024.06.002 (IF = 13.0) （2025年ESI高被引文章）
42. Yuer Lu, Yongfa Ying, Chen Lin, Yan Wang, Jun Jin, Xiaoming Jiang, Qi Zhao, Jianwei Shuai, Xiang Li, Jinjin Zhong. UNet-Att: A Self-supervised Denoising and Recovery Model for Two-Photon Microscopic Image. Complex & Intelligent Systems, 2025, 11：55, https://doi.org/10.1007/s40747-024-01633-7 (IF = 4.6)
41. Yinda Chen, Shuo Pan, Yu Xia, Keqi Ren, Luying Zhang, Zefei Mo, Jiahe Chen, Meijia Zhang, Huanhuan Li, Jianwei Shuai, Qinghua Xia, Rongwen Yu. A Conversational Application for Insomnia Treatment: Leveraging the ChatGLM-LoRA Model for Cognitive Behavioral Therapy. 2024 IEEE International Conference on Cybernetics and Intelligent Systems (CIS) and IEEE International Conference on Robotics, Automation and Mechatronics (RAM). CIS-RAM 2024: 360-367
40. Jing Wang, Gao Wang, Huaicheng Chen, Yanping Liu, Peilong Wang, Daming Yuan, Xingyu Ma, Xiangyu Xu, Zhengdong Cheng, Baohua Ji, Mingcheng Yang, Jianwei Shuai, Fangfu Ye, Jin Wang, Yang Jiao & Liyu Liu, Robo-Matter towards reconfigurable multifunctional smart materials, Nature Communications. 2024, 15: 8853, https://doi.org/10.1038/s41467-024-53123-6 (IF =15.7 )
39. Qingzu He, Huan Guo, Yulin Li, Guoqiang He, Xiang Li, Jianwei Shuai. SeFilter-DIA: Squeeze-and-excitation network for filtering high-confidence peptides of data-independent acquisition proteomics. Interdisciplinary Sciences: Computational Life Sciences. 2024, 16, 579-592 https://doi.org/10.1016/j.fmre.2024.02.009 (IF = 3.9)
38. Yuer Lu, Yongfa Ying, Chengliang Huang, Xiang Li, Jinyan Cheng, Rongwen Yu, Lixiang Ma, Jianwei Shuai, Xuejin Zhou, Jinjin Zhong. STORM: Image Denoising and Information Extraction. Biomedical Physics & Engineering Express. 2024, 10: 065028 DOI 10.1088/2057-1976/ad7a02, (IF = 1.6)
37. Yinping Zhai, Darong Hai, Li Zeng, Chenyan Lin, Xinru Tan, Zefei Mo, Qijia Tao, Wenhui Li, Xiaowei Xu, Qi Zhao, Jianwei Shuai, Jingye Pan, Artificial intelligence-based evaluation of prognosis in cirrhosis, Journal of Translational Medicine, 2024, 22: 933， https://doi.org/10.1186/s12967-024-05726-2（IF = 7.5）
36. Qingzu He, Xiang Li, Jinjin Zhong, Gen Yang, Jiahuai Han, Jianwei Shuai, Dear‐PSM: A deep learning‐based peptide search engine enables full database search for proteomics, Smart Medicine. 2024, e20240014. https://doi.org/10.1002/SMMD.20240014 (IF = 11.6)
35. Guoqiang He, Qingzu He, Jinyan Cheng, Rongwen Yu, Jianwei Shuai and Yi Cao. ProPept-MT: A Multi-Task Learning Model for Peptide Feature Prediction. International Journal of Molecular Science. 2024, 25: 7237 1-20. https://doi.org/10.3390/ijms25137237 （IF=4.9）
34. Yanping Liu, Yang Jiao, Xinwei Li, Guoqiang Li, Wei Wang, Zhichao Liu, Dui Qin, Lisha Zhong, Liyu Liu, Jianwei Shuai, Zhangyong Li. An Entropy-Based Approach for Assessing the Directional Persistence of Cell Migration. Biophysical Journal, 2024 123: 730-744, https://doi.org/10.1016/j.bpj.2024.02.010 (IF = 3.1)
33. Hai Lin, Huan Hu, Zhen Feng, Fei Xu, Jie Lyu, Xiang Li, Liyu Liu, Gen Yang, Jianwei Shuai, SCTC: inference of developmental potential from single-cell transcriptional complexity, Nucleic Acids Research, 2024, 52, 6114-6128. https://doi.org/10.1093/nar/gkae340 (IF =17)
32. Fangfang Zhu, Qichao Niu, Xiang Li, Qi Zhao, Honghong Su, and Jianwei Shuai. FM-FCN: A Neural Network with Filtering Modules for Accurate Vital Signs Extraction. Research 2024, 7: 0361. https://doi.org/10.34133/research.0361 (IF = 10.7) （2025年ESI高被引文章）
31. Jinjin Zhong, Ling Li, Sarah Kariko, Long Zhang, Zhengyong Song, Xiang Li, Yuer Lu, Zhengdong Cheng, Jianwei Shuai. Doublet Nanoplate Structure of Phoroncidia rubroargentea Spider-Derived Guanine Crystals for Enhanced Broadband Reflectivity. ACS Applied Nano Materials. 2024, 7: 6487-6498. https://doi.org/10.1021/acsanm.4c00252 (IF = 5.5)
30. Xiang Li, Min Wu, Jianwei Shuai, Clovibactin: A revolutionary antibiotic unleashing lethal efficacy against pathogens with little drug resistance, Science Bulletin 2024 69: 570-573. doi: 10.1016/j.scib.2023.12.047. (IF=21.1)
29. Fangfang Zhu, Zhenhao Shuai, Yuer Lu, Honghong Su, Rongwen Yu, Xiang Li, Qi Zhao, Jianwei Shuai, oBABC: A one-dimensional binary artificial bee colony algorithm for binary optimization, Swarm and Evolutionary Computation, 2024，87, 101567, https://doi.org/10.1016/j.swevo.2024.101567. (IF = 8.5) （2025年ESI高被引文章）
28. Xinlong Xing, Xiaosen Li, Chaoyi Wei, Zhantian Zhang, Ou Liu, Senmiao Xie, Haoman Chen, Shichao Quan, Cong Wang, Xin Yang, Xiaoming Jiang, Jianwei Shuai. DP-GAN+B: A lightweight generative adversarial network based on depthwise separable convolutions for generating CT volumes. Computers in Biology and Medicine, 2024, 174: 108393. https://doi.org/10.1016/j.compbiomed.2024.108393 (IF = 6.3)
27. Jing Wang, Yao Zhou, Meng Zhang, Yujiao Wu, Qun Wu, Wen Su, Min Xu, Jinhong Wu, Min Zhang, Jianwei Shuai, Wei Tang, Jiajia Lv, Min Wu, Zhenwei Xia, YTHDF1-CLOCK axis contributes to pathogenesis of allergic airway inflammation through LLPS, Cell Reports, 2024, 43(3): 113947, https://doi.org/10.1016/j.celrep.2024.113947. (IF = 6.9)
26. Fei Xu, Huan Hu, Jun Lu, Feng Cheng, Jiqian Zhang, Qi Zhao, Xiang Li, Jianwei Shuai. scGIR: deciphering cellular heterogeneity via gene ranking in single-cell weighted gene correlation networks. Briefings in Bioinformatics, 2024, 25: bbae091 https://doi.org/10.1093/bib/bbae091 (IF = 7.7)
25. Yanping Liu, Yang Jiao, Qihui Fan, Xinwei Li, Zhichao Liu, Dui Qin, Jun Hu, Liyu Liu, Jianwei Shuai, Zhangyong Li. Morphological Entropy Encodes Cellular Migration Strategies on Multiple Length Scales. NPJ Systems Biology and Applications. 2024, 10: 26. https://doi.org/10.1038/s41540-024-00353-5 (IF = 3.5)
24. Yulin Li, Qingzu He, Huan Guo, Stella C Shuai, Jinyan Cheng, Liyu Liu, Jia Shuai. AttnPep: A Self-Attention-Based Deep Learning Method for Peptide Identification in Shotgun Proteomics. Journal of Proteome Research. 2024, 23: 834-843. DOI:10.1021/acs.jproteome.3c00729 (IF = 3.6)
23. Jun Jin, Fei Xu, Zhilong Liu, Jianwei Shuai, Xiang Li, Quantifying the underlying landscape, entropy production and biological path of the cell fate decision between apoptosis and pyroptosis, Chaos, Solitons and Fractals, 2024, 178: 114328, doi.org/10.1016/j.chaos.2023.114328 (IF=5.6)
22. Fangfang Zhu, Ji Ding, Xiang Li, Yuer Lu, Xiao Liu, Frank Jiang, Qi Zhao, Honghong Su, Jianwei Shuai, MEAs-Filter: a novel filter framework utilizing evolutionary algorithms for cardiovascular diseases diagnosis, Health Information Science and Systems, 2024, 12: 8. https://doi.org/10.1007/s13755-023-00268-1 (IF=3.4) （2025年ESI高被引论文）
21. Jingru Yao, Guoqiang Li, Lianjie Zhou, Shuyan Xu, Kena Song, Hongfei Zhang, Xianquan Zhang, Jianwei Shuai, Fangfu Ye, Ming Li, Guo Chen, He Liu, Peter Shaw, Liyu Liu. 3-D collagen microchamber arrays for combined chemotherapy effect evaluation on cancer cell numbers and migration. Biomicrofluidics. 2023, 17: 014101. DOI: 10.1063/5.0121952 (IF = 2.4)
20. Jun Jin, Fei Xu, Zhilong Liu, Hong Qi, Chenggui Yao, Jianwei Shuai, and Xiang Li. Biphasic amplitude oscillator characterized by distinct dynamics of trough and crest. Phys. Rev. E 2023, 108: 064412， https://doi.org/10.1103/PhysRevE.108.064412 (IF = 2.4)
19. Xiaosen Li, Xiao Qin, Chengliang Huang, Yuer Lu, Jinyan Cheng, Liansheng Wang, Ou Liu, Jianwei Shuai, Chang-an Yuan, SUnet: A Multi-organ Segmentation Network based on Multiple Attention, Computers in Biology and Medicine 2023, 167: 107596 https://doi.org/10.1016/j.compbiomed.2023.107596 (IF=6.3)
18. Dezhen Qi, Jun Xie, Guoyu Yang, Dongdong Liu, Ye Qiu, Yuer Lu, Xiaoming Jiang, Jianwei Shuai, CaT: Cyclic-Accumulation Transformer for Lane Detection, 2023 International Joint Conference on Neural Networks (IJCNN), Gold Coast, Australia, 2023, pp. 1-8, doi: 10.1109/IJCNN54540.2023.10191407
17. Haoman Chen, Hui Ye, Fanxuan Chen, Yi Shi, Jiahe Li, Yuhang Li, Chaoyi Wei, Chengxi Zhang, Jinhao Jin, Quanyue Zhang, Shuo Pan, Dong Chen, Shichao Quan, Xiaowei Xu, Zongxing Yang, Lijun Xu, Yungui Zhang, Yi Wang, Yunlong Zhou, Ou Liu, Xiaoming Jiang, Liyu Liu, Qingzu He, Xiaoqu Hu, Jingye Pan, Jianwei Shuai, Feifei Su. Revolutionizing Infection Risk Scoring: An Ensemble “From Weak to Strong” Deduction Strategy and Enhanced Point-of-Care Testing Tools. Advanced Intelligent Systems. 2023, 2300224 1-13, https://doi.org/10.1002/aisy.202300224 (IF = 6.1)
16. Yunlong Ma, Chunyu Deng, Yijun Zhou, Yaru Zhang, Fei Qiu, Dingping Jiang, Gongwei Zheng, Jingjing Li, Jianwei Shuai, Yan Zhang, Jian Yang, and Jianzhong Su. Polygenic regression uncovers trait-relevant cellular contexts through pathway activation transformation of single-cell RNA sequencing data. Cell Genomics, 2023, 3: 100383. https://doi.org/10.1016/j.xgen.2023.100383 （IF = 9）
15. Hongyan Gao, Jianqiang Sun, Yukun Wang, Yuer Lu, Liyu Liu, Qi Zhao, and Jianwei Shuai. Predicting metabolite–disease associations based on auto-encoder and non-negative matrix factorization. Briefings in Bioinformatics, 2023, 24: bbad259 1–13, https://doi.org/10.1093/bib/bbad259 (IF = 7.7) （2024年ESI高被引文章）
14. Huan Hu, Zhen Feng, Xinghao Steven Shuai, Jie Lyu, Xiang Li, Hai Lin and Jianwei Shuai. Identifying SARS-CoV-2 infected cells with scVDN. Frontiers in Microbiology. 2023, 14: 1236653. doi: 10.3389/fmicb.2023.1236653, (IF = 4.5)
13. Fei Xu, Dingyang Miao, Wei Li, Jun Jin, Zhilong Liu, Chuansheng Shen, Jiqian Zhang, Jianwei Shuai, and Xiang Li. Specificity and competition of mRNAs dominate droplet pattern in protein phase separation. Physical Review Research 2023, 5: 023159. (IF=4.2)
12. Hong Qi, Yu-Song Yin, Zhi-Yong Yin, Xiang Li, Jian-Wei Shuai. Mitochondrial outer membrane permeabilization and inner membrane permeabilization in regulating apoptosis and inflammation. Journal of Theoretical Biology 2023, 571: 111558. https://doi.org/10.1016/j.jtbi.2023.111558 (IF=2.0)
11. Chenggui Yao, Fei Xu, Xiangdong Tang, Wei Zou, Dongping Yang, Jianwei Shuai. A physical understanding and quantification for the regulation of orexin on sleep. Chaos 2023, 33: 073119. https://doi.org/10.1063/5.0156090 (IF=3.2)
10. Qingzu He, Chuan-Qi Zhong, Xiang Li, Huan Guo, Yiming Li, Mingxuan Gao, Rongshan Yu, Xianming Liu, Fangfei Zhang, Tiannan Guo, Donghui Guo, Fangfu Ye, Jianwei Shuai, and Jiahuai Han, Dear-DIAXMBD: deep autoencoder for data-independent acquisition proteomics. Research 2023, 6: 0179. DOI: 10.34133/research.0179. (IF=10.7)
9. Chenggui Yao, JianQiang Sun, Jun Jin, Jianwei Shuai, Xiang Li, Yuangen Yao, Xufan Xu， The power law statistics of the spiking timing in a neuronal network, Chaos, Solitons and Fractals, 2023, 172: 113598. (IF=5.6)
8. 郭欢, 何情祖, 黎玉林, 帅建伟. 深度神经网络筛选蛋白质组学高置信度定量肽段. 生物物理学, 2023, 11(2): 17-29.
7. Jianwei Shuai. Editorial: The pathogenesis and intervention of sleep disorders. Frontiers in Neuroscience, 2023, 17: 1176932. doi: 10.3389/fnins.2023.1176932 (IF=3.2)
6. Jiacheng Wang, Fei Chen, Yuxi Ma, Liansheng Wang, Zhaodong Fei, Jianwei Shuai, Xiangdong Tang, Qichao Zhou, Jing Qin. XBound-Former: Toward Cross-scale Boundary Modeling in Transformers. IEEE Transactions on Medical Imaging 2023, 42(6): 1735-1745. doi: 10.1109/TMI.2023.3236037 (IF = 9.8)
5. 袁钦湄，杨峘，张骏，刘博雯，帅建伟，曹玉萍. 基于深度学习算法的抑郁症表情与动作及其心理整合变化的过程分析. 中国临床心理学杂志. 2023, 31(1): 241
4. Huan Hu, Zhen Feng, Hai Lin, Jinyan Cheng, Jie Lyu, Yaru Zhang, Junjie Zhao, Fei Xu, Tao Lin, Qi Zhao, Jianwei Shuai. Gene function and cell surface protein association analysis based on single-cell multiomics data. Computers in Biology and Medicine. 2023, 157, 106733, https://doi.org/10.1016/j.compbiomed.2023.106733. (IF=6.3) （2024年ESI高被引文章）
3. Huan Hu, Zhen Feng, Hai Lin, Junjie Zhao, Yaru Zhang, Fei Xu, Lingling Chen, Feng Chen, Yunlong Ma, Jianzhong Su, Qi Zhao, Jianwei Shuai. Modeling and analyzing single-cell multimodal data with deep parametric inference. Briefings in Bioinformatics, 2023, 24(1): bbad005. https://doi.org/10.1093/bib/bbad005 (IF= 7.7) （2024年ESI高被引文章）
2. Jingxuan Zhao, Jianqiang Sun, Stella C Shuai, Qi Zhao1, Jianwei Shuai, Predicting potential interactions between lncRNAs and proteins via combined graph auto-encoder methods, Briefings in Bioinformatics 2023, 24(1), bbac527, 1-9, https://doi.org/10.1093/bib/bbac527 (IF= 7.7)
1. Chaoyi Wei, Xinli Xiang, Xiaobo Zhou, Siyan Ren, Qingyu Zhou, Wenjun Dong, Haizhen Lin, Saijun Wang, Yuyue Zhang, Hai Lin, Qingzu He, Yuer Lu, Xiaoming Jiang, Jianwei Shuai, Xiance Jin, Congying Xie. Development and validation of an interpretable radiomic nomogram for severe radiation proctitis prediction in postoperative cervical cancer patients. Frontiers in Microbiology. 2023, 13: 1090770. Doi: 10.3389/fmicb.2022.1090770. (IF = 4.5)
研究成果
交流合作
课题组积极开展国内外学术交流与合作，建立了广泛的合作网络，推动科研成果的转化和应用。