ShuaiAI课题组

About Lab

Our research group focuses on intelligent mechanics, biomedical modeling, multi omics big data analysis, artificial intelligence deep learning, and has achieved a series of important academic value research results in cell signal networks, single-cell multi omics analysis, protein mass spectrometry analysis, health and medical big data, and cancer cell dynamics modeling.

Latest Publications

Briefings
In
Bioinformatics
January, 2023.

Modeling and analyzing single-cell multimodal data with deep parametric inference

Huan Hu; Zhen Feng; Hai Lin; Junjie Zhao; Yaru Zhang; Fei Xu; Lingling Chen; Feng Chen; Yunlong Ma; Jianzhong Su; Qi Zhao; Jianwei Shuai.

ACS Applied
Materials & Interfaces
July, 2022.

Assembly of Guanine Crystals as a Low-Polarizing Broadband Multilayer Reflector in a Spider, Phoroncidia rubroargentea.

Jinjin Zhong; Zhengyong Song; Long Zhang; Xiang Li; Qingzu He; Yuer Lu; Sarah Kariko; Peter Shaw; Liyu Liu; Fangfu Ye; Ling Li; Jianwei Shuai.

Research
July, 2022.

Caspase-1 and Gasdermin D Afford the Optimal Targets with Distinct Switching Strategies in NLRP1b Inflammasome-Induced Cell Death.

Xiang Li; Peipei Zhang; Zhiyong Yin; Fei Xu; Zhang-Hua Yang; Jun Jin; Jing Qu; Zhilong Liu; Hong Qi; Chenggui Yao; Jianwei Shuai.

Nature
Cell
Biology
March, 2022.

Mosaic composition of RIP1–RIP3 signalling hub and its role in regulating cell death.

Xin Chen; Rongfeng Zhu; Jinjin Zhong; Yongfa Ying; Wenxin Wang; Yating Cao; Hanyi Cai; Xiang Li; Jianwei Shuai; Jiahuai Han.

Protein
&
Cell
November 2021.

RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes.

Li Xiang; Zhong Chuanqi; Wu Rui; Xu Xiaozheng; Yang Zhanghua; Cai Shaowei; Wu Xiurong; Chen Xin; Yin Zhiyong; He Qingzu; Li Dianjie; Xu Fei; Yan Yihua; Qi Hong; Xie Changchuan; Shuai Jianwei; Han Jiahuai.